Search Results
Overview
| Uniprot ID | A0A286ZT79 |
|---|---|
| Protein Name | DNA-directed RNA polymerases I and III subunit RPAC1 |
| Gene Name | POLR1C |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 140 | TRNPSAAKDSSDPNE |
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft
Protein Sequence
10
MGTPISHVLN
20
EWKVKTRSLS
30
QKLMKDWRRK
40
KHPNFRVDVV
50
HMDENSLEFD
60
MVGIDAAIAN
70
AFRRILLAEV
80
PTMAVEKVLV
90
YNNTSIVQDE
100
ILAHRLGLIP
110
IHADPRLFEY
120
RNLGDEEGTE
130
IDTLQFRLQV
140
RCTRNPSAAK
150
DSSDPNELYV
160
NHKVYTRHMT
170
WVPLGNQADL
180
FPEGTIRPVH
190
DDILIAQLRP
200
GQEIDLLMQC
210
VKGIGKDHAK
220
FSPVATASYR
230
LLPDITLLEP
240
VEGDAAEELS
250
RCFSPGVIEV
260
QEIQGKKVAR
270
VANPRLDTFS
280
REVFRNDMLK
290
KVVRLARVRD
300
HYIFSVESTG
310
VLPPDVLVSE
320
AIKVLMGKCR
330
RFLDELDAVQ
MD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005736 | RNA polymerase I complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003899 | DNA-directed RNA polymerase activity |
| Molecular Function | GO:0046983 | protein dimerization activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.