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Overview

Uniprot IDA0A286ZTK8
Protein Namemitogen-activated protein kinase kinase
Gene NameMAP2K3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
142 GAYGVVEKVRHAQSG
262 PSNVLINKEGHVKMC

Function

No function data available.

Protein Sequence

10 MRGPVWLLQR 20 RGPEGWGGSR 30 APRLLGAFPG 40 QPAYPPSSPC 50 SLVLCLFCGR 60 RGEAQWACRT 70 GPGAPSRMRL 80 LQDWSTDQPG 90 WWPSLSAAPA 100 PLLDGVWGVR 110 AGTCLGPRGP 120 SLSSVPKNFE 130 VEADDLVTIS 140 ELGRGAYGVV 150 EKVRHAQSGT 160 IMAVKRIRAT 170 VNSQEQKRLL 180 MDLDVNMRTV 190 DCFYTVTFYG 200 ALFREGDVWI 210 CMELMDTSLD 220 KFYRKVLEKN 230 MTIPEDILGE 240 IAVSIVRALE 250 HLHSKLSVIH 260 RDVKPSNVLI 270 NKEGHVKMCD 280 FGISGYLVDS 290 VAKTMDAGCK 300 PYMAPERINP 310 ELNQKGYNVK 320 SDVWSLGITM 330 IEMAILRFPY 340 ESWGTPFQQL 350 KQVVEEPSPQ 360 LPADRFSPEF 370 VDFTAQCLRK 380 NPAERMSYLE 390 LMVSVGGALG 400 GAAAWALPPS 410 FRELHHSFTR 420 MYPGPVEGGR 430 GRPGGPCHVQ 440 AFGKALQGNR A

Gene Ontology

Classification GO ID Description
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004708 MAP kinase kinase activity
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0004674 protein serine/threonine kinase activity
Biological Process GO:0035924 cellular response to vascular endothelial growth factor stimulus
Biological Process GO:0035331 negative regulation of hippo signaling
Biological Process GO:0038066 p38MAPK cascade
Biological Process GO:0043536 positive regulation of blood vessel endothelial cell migration
Biological Process GO:0045893 positive regulation of DNA-templated transcription
Biological Process GO:0031098 stress-activated protein kinase signaling cascade

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.