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Overview

Uniprot ID	A0A286ZU91
Protein Name	Vacuolar protein sorting-associated protein 35
Gene Name	VPS35
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
20	KRCLDKNKLMDALKH
401	ILTVLKLKHFHPLFE
534	ENSKVDDKWEKKCQK
641	QCALAASKLLKKPDQ

Function

Plays a role in vesicular protein sorting

Protein Sequence

10 AIQAVKVQSF 20 QMKRCLDKNK 30 LMDALKHASN 40 MLGELRTSML 50 SPKSYYELYM 60 AISDELHYLE 70 VYLTDEFAKG 80 RKVADLYELV 90 QYAGNIIPRL 100 YLLITVGVVY 110 VKSFPQSRKD 120 ILKDLVEMCR 130 GVQHPLRGLF 140 LRNYLLQCTR 150 NILPDEGEPT 160 DEETTGDISD 170 SMDFVLLNFA 180 EMNKLWVRMQ 190 HQGHSRDREK 200 RERERQELRI 210 LVGTNLVRLS 220 QLEGVNVERY 230 KQIVLTGILE 240 QVVNCRDALA 250 QEYLMECIIQ 260 VFPDEFHLQT 270 LNPFLRACAE 280 LHQNVNVKNI 290 IIALIDRLAL 300 FAHREDGPGI 310 PADIKLFDIF 320 SQQVATVIQS 330 RQDMPSEDVV 340 SLQVSLINLA 350 MKCYPDRVDY 360 VDKVLETTVE 370 IFNKLNLEHI 380 ATSSAVSKEL 390 TRLLKIPIDT 400 YNNILTVLKL 410 KHFHPLFEYF 420 DYESRKSMSC 430 YVLSNVLDYN 440 TEIVSQDQVD 450 SIMNLVSTLI 460 QDQPDQPAED 470 PDPEDFADEQ 480 SLVGRFIHLL 490 RSEDPDQQYL 500 ILNTARKHFG 510 AGGNQRIRFT 520 LPPLVFAAYQ 530 LAFRYKENSK 540 VDDKWEKKCQ 550 KIFSFAHQTI 560 SALIKAELAE 570 LPLRLFLQGA 580 LAAGEIGFEN 590 HETVAYEFMS 600 QAFSLYEDEI 610 SDSKAQLAAI 620 TLIIGTFERM 630 KCFSEENHEP 640 LRTQCALAAS 650 KLLKKPDQGR 660 AVSTCAHLFW 670 SGRNTDKNGE EVRWQGWSF

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0030906	retromer, cargo-selective complex
Biological Process	GO:0015031	protein transport
Biological Process	GO:0042147	retrograde transport, endosome to Golgi

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.