Search Results
Overview
| Uniprot ID | A0A286ZV67 |
|---|---|
| Protein Name | 3-phosphoinositide-dependent protein kinase 1 |
| Gene Name | PDPK1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 223 | TSREYAIKILEKRHI |
| 435 | LLVLDATKRLGCEEM |
Function
No function data available.
Protein Sequence
10
MFGPAFSVDR
20
AWSQRMSRPG
30
REMGRPAGRG
40
RAGSRVGGGG
50
RGRGQMGAAG
60
QGPWAPRTRQ
70
VGAEQGRDLE
80
RRAAAPTARR
90
SGDGLPSIGG
100
VSSAPVLCSR
110
SLARVSHAPS
120
PSPSLCPQYD
130
AAPVQSSVVL
140
CSCPSPSMVR
150
TQTESSAAPG
160
VPSGGSRQGP
170
TMDSTAAEAR
180
PNTRSLQHAA
190
QPPPQPRKKR
200
PEDFKFGKIL
210
GEGSFSTVVL
220
ARELATSREY
230
AIKILEKRHI
240
IKENKVPYVT
250
RERDVMSRLD
260
HPFFVKLYFT
270
FQDDEKLYFG
280
LSYAKNGELL
290
KYIRKIGSFD
300
ETCTRFYTAE
310
MVSALEYLHG
320
KGIIHRDLKP
330
ENILLNEDMH
340
IQITDFGTAK
350
VLSPESKQAR
360
ANSFVGTAQY
370
VSPELLTEKS
380
ACKSSDLWAL
390
GCIIYQLVAG
400
LPPFRAGNEY
410
LIFQKIIKLE
420
YDFPEKFFPK
430
ARDLVEKLLV
440
LDATKRLGCE
450
EMGGYSPLKA
460
HAFFESVMWE
470
NLHHQTPPKL
480
TAYLPAMSED
490
DEDCYGNYDN
500
LLSQFGCMQV
510
SSSPSSQSLS
520
AVDAGLPQRA
530
GSNIEQYIHD
540
LDTNSFELDL
550
QFSEDEKRLL
560
LEKQASGNPW
570
HQFVENNLIL
580
KMGPVDKRKG
590
LFARRRQLLL
600
TEGPHLYYVD
610
PVNKVLKGEI
620
PWSQELRPEA
630
KNFKTFFVHT
640
PNRTYYLMDP
650
SGNAHKWCKK
660
IQEVWRHRYQ
SHPDAAVQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0007173 | epidermal growth factor receptor signaling pathway |
| Biological Process | GO:0097191 | extrinsic apoptotic signaling pathway |
| Biological Process | GO:0008286 | insulin receptor signaling pathway |
| Biological Process | GO:0048009 | insulin-like growth factor receptor signaling pathway |
| Biological Process | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process |
| Biological Process | GO:2000352 | negative regulation of endothelial cell apoptotic process |
| Biological Process | GO:0034122 | negative regulation of toll-like receptor signaling pathway |
| Biological Process | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process | GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0043536 | positive regulation of blood vessel endothelial cell migration |
| Biological Process | GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:1903078 | positive regulation of protein localization to plasma membrane |
| Biological Process | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol |
| Biological Process | GO:1903672 | positive regulation of sprouting angiogenesis |
| Biological Process | GO:1905564 | positive regulation of vascular endothelial cell proliferation |
| Biological Process | GO:0043122 | regulation of canonical NF-kappaB signal transduction |
| Biological Process | GO:0043304 | regulation of mast cell degranulation |
| Biological Process | GO:0003323 | type B pancreatic cell development |
| Cellular Component | GO:0042995 | cell projection |
| Cellular Component | GO:0031410 | cytoplasmic vesicle |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0014069 | postsynaptic density |
| Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016004 | phospholipase activator activity |
| Molecular Function | GO:0043274 | phospholipase binding |
| Biological Process | GO:0019722 | calcium-mediated signaling |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:0006351 | DNA-templated transcription |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.