Search Results
Overview
| Uniprot ID | A0A286ZW70 |
|---|---|
| Protein Name | Peptidyl-prolyl cis-trans isomerase |
| Gene Name | PPIB |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 116 | RGDGTGGKSIYGERF |
| 129 | RFPDENFKLKHYGPG |
| 131 | PDENFKLKHYGPGWV |
| 165 | KTAWLDGKHVVFGKV |
| 171 | GKHVVFGKVLEGMEV |
| 195 | DGRDKPLKDVTIADC |
| 209 | CGKIEVEKPFAIAKE |
| 215 | EKPFAIAKE****** |
| 41 | DEKKKGPKVTVKVYF |
| 67 | VVIGLFGKTVPKTVD |
| 71 | LFGKTVPKTVDNFVA |
| 89 | GEKGFGYKNSKFHRV |
Function
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding
Protein Sequence
10
MLRFLERNMK
20
VLFVAAVVVG
30
SVLFLLLPGP
40
STADEKKKGP
50
KVTVKVYFDL
60
RIGDEDIGRV
70
VIGLFGKTVP
80
KTVDNFVALA
90
TGEKGFGYKN
100
SKFHRVIKDF
110
MIQGGDFTRG
120
DGTGGKSIYG
130
ERFPDENFKL
140
KHYGPGWVSM
150
ANAGKDTNGS
160
QFFITTVKTA
170
WLDGKHVVFG
180
KVLEGMEVVR
190
KVESTKTDGR
200
DKPLKDVTIA
210
DCGKIEVEKP
FAIAKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0034663 | endoplasmic reticulum chaperone complex |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0016018 | cyclosporin A binding |
| Molecular Function | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity |
| Molecular Function | GO:0070063 | RNA polymerase binding |
| Biological Process | GO:0060348 | bone development |
| Biological Process | GO:0044829 | host-mediated activation of viral genome replication |
| Biological Process | GO:0030593 | neutrophil chemotaxis |
| Biological Process | GO:0040018 | positive regulation of multicellular organism growth |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0050821 | protein stabilization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.