Search Results
Overview
| Uniprot ID | A0A286ZX58 |
|---|---|
| Protein Name | Rap1 GTPase-GDP dissociation stimulator 1 |
| Gene Name | RAP1GDS1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 310 | QKLFEGGKGNVFQRV |
| 391 | LAIPVVNKAKMLSAG |
| 585 | KLRGHENKSVAQQAS |
Function
Acts as a GEF (guanine nucleotide exchange factor) for prenylated RHOA. Acts as a GEF for RHOC. Chaperones the downstream trafficking and/or processing of small newly prenylated GTPases. Escorts RAC1 to the nucleus
Protein Sequence
10
IDTLKKLKIT
20
AVDRTDDSLE
30
GCLDCLLQAL
40
AQNNTETSEK
50
IQGSGILHLF
60
SSLLIPQSSC
70
TAKVANIIAE
80
LAKNEFMRIP
90
CVDAGLISPL
100
VQLLNSKDQE
110
VLLQTGRALG
120
NICYDSHEGR
130
SAVDQAGGAQ
140
IVVDHLRSLC
150
SITDPANEKL
160
LTVFCGMLMN
170
YSNENDSLQA
180
QLINMGVIPT
190
LVKLLGIHCQ
200
NAALTEMCLV
210
AFGNLAELES
220
SKEQFASTNI
230
AEELVKLFKK
240
QIEHDKREMI
250
FEVLAPLAEN
260
DAIKLQLVEA
270
GLVECLLEIV
280
QQKVDSDKEE
290
DIAELKTASD
300
LMVLLLLGDE
310
SMQKLFEGGK
320
GNVFQRVLSW
330
IPSNNHQLQL
340
AGALAIANFA
350
RNDGNCIHMV
360
DNGIVEKLMD
370
LLDRHVEDGN
380
VTVQHAALSA
390
LRNLAIPVVN
400
KAKMLSAGVT
410
EAVLKFLKSE
420
MPPVQFKLLG
430
TLRMLIDAQE
440
AAEQLGKNVK
450
LVERLVEWCE
460
AKDHAGVMGE
470
SNRLLSALIR
480
HSKSKDVIKT
490
IVQSGGIKHL
500
VTMATSEHVI
510
MQNEALVALA
520
LIAALELGTA
530
EKDLESAKLV
540
QILHRLLADE
550
RSAPEIKYNS
560
MVLICALMGS
570
ESLHKEVQDL
580
AFLDVVSKLR
590
GHENKSVAQQ
600
ASLTEQRLAV
ES
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0005085 | guanyl-nucleotide exchange factor activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.