Search Results

Overview

Uniprot IDA0A286ZXX4
Protein NameProteasome assembly chaperone 2
Gene NamePSMG2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
100 IFIKYKSKSFCEKLL
111 EKLLSWVKSSDLAKV
117 VKSSDLAKVVVLSSS
84 VYASPSKKLVALQLR

Function

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization

Protein Sequence

10 MFVPCGDSVP 20 DLAGCTLLMP 30 AVSVGNVGQL 40 AIDLIISTLN 50 MCKIGYFYTD 60 CLVPMVGNNP 70 YATAEENSTE 80 LSINAEVYAS 90 PSKKLVALQL 100 RSIFIKYKSK 110 SFCEKLLSWV 120 KSSDLAKVVV 130 LSSSHSYQRN 140 DLQLRSTPFR 150 YLLTPSIPKS 160 VQNKIQSLNW 170 EEMEKSPCIP 180 EIDDSEFCVR 190 VPGGGITKTL 200 YDEGCSKGIP 210 MAVLLKFVSE 220 GDNIPDALGL 230 VEYLNEWLQI 240 IKPCCEDTTE 250 SALPWKMPSS 260 WRLLFGSGLP PALF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005634 nucleus
Molecular Function GO:0060090 molecular adaptor activity
Biological Process GO:0043248 proteasome assembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.