Search Results
Overview
| Uniprot ID | A0A286ZY98 |
|---|---|
| Protein Name | DNA-directed RNA polymerases I and III subunit RPAC1 |
| Gene Name | POLR1C |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 118 | TRNPSAAKDSSDPNE |
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft
Protein Sequence
10
MNLASLLLRE
20
QNFRVDVVHM
30
DENSLEFDMV
40
GIDAAIANAF
50
RRILLAEVPT
60
MAVEKVLVYN
70
NTSIVQDEIL
80
AHRLGLIPIH
90
ADPRLFEYRN
100
LGDEEGTEID
110
TLQFRLQVRC
120
TRNPSAAKDS
130
SDPNELYVNH
140
KVYTRHMTWV
150
PLGNQADLFP
160
EGTIRPVHDD
170
ILIAQLRPGQ
180
EIDLLMQCVK
190
GIGKDHAKFS
200
PVATASYRLL
210
PDITLLEPVE
220
GDAAEELSRC
230
FSPGVIEVQE
240
IQGKKVARVA
250
NPRLDTFSRE
260
VFRNDMLKKV
270
VRLARVRDHY
280
IFSVESTGVL
290
PPDVLVSEAI
300
KVLMGKCRRF
310
LDELDAVQMD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005736 | RNA polymerase I complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003899 | DNA-directed RNA polymerase activity |
| Molecular Function | GO:0046983 | protein dimerization activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.