Overview
| Uniprot ID | A0A286ZYL7 |
|---|
| Protein Name | ATP synthase F(1) complex subunit delta, mitochondrial |
|---|
| Gene Name | ATP5F1D |
|---|
| Organism | Sus scrofa |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 136 |
VAKANLEKAQSELLG |
Function
Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. With the central stalk subunit gamma, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate
Protein Sequence
10
MLPATLLRRS
20
GLGRVVRQAR
30
AYAEAAAAPA
40
SAAGPGQMSF
50
TFASPTQVFF
60
NGANVRQVDV
70
PTQTGAFGIL
80
ASHVPTLQVL
90
RPGLVVVHAE
100
DGTTSKYFVS
110
SGSVTVNADS
120
SVQLLAEEAV
130
TLDMLDPGVA
140
KANLEKAQSE
150
LLGAADEASR
160
AEIQIRIEAN
EALVKALE
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0005743 |
mitochondrial inner membrane |
| Cellular Component |
GO:0045259 |
proton-transporting ATP synthase complex |
| Molecular Function |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.