Search Results
Overview
| Uniprot ID | A0A286ZZM7 |
|---|---|
| Protein Name | Thioredoxin domain-containing protein 17 |
| Gene Name | TXNDC17 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 40 | GSKDAEGKSWCPDCV |
| 78 | VGERLYWKDPNNDFR |
| 89 | NDFRKKLKLTAVPTL |
| 98 | TAVPTLLKYGTPQKL |
Function
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide
Protein Sequence
10
MARYEEVSVS
20
GYEEFIQAVK
30
QHNGKTIFAY
40
FSGSKDAEGK
50
SWCPDCVQAE
60
PVVREGLKHT
70
VEGCVFIYCQ
80
VGERLYWKDP
90
NNDFRKKLKL
100
TAVPTLLKYG
110
TPQKLVESEC
120
LQTNLVEMLF
SEE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0004601 | peroxidase activity |
| Molecular Function | GO:0047134 | protein-disulfide reductase [NAD(P)H] activity |
| Biological Process | GO:0033209 | tumor necrosis factor-mediated signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.