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Overview

Uniprot IDA0A287A0V4
Protein NameThioredoxin-like protein
Gene NameTXNL4A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
134 RGLVVSPKDYSTKYR

Function

Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex)

Protein Sequence

10 MSYMLPHLHN 20 GWQVDQAILS 30 EEDRVVVIRF 40 GHDWDPTCMK 50 MDEVLYSIAE 60 KVKNFAVIYL 70 VDITEVPDFN 80 KMYELYDPCT 90 VMFFFRNKHI 100 MIDLGTGNNN 110 KINWAMEDKQ 120 EMIDIIETVY 130 RGARKGRGLV 140 VSPKDYSTKY RY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005681 spliceosomal complex
Cellular Component GO:0046540 U4/U6 x U5 tri-snRNP complex
Cellular Component GO:0005682 U5 snRNP
Biological Process GO:0000398 mRNA splicing, via spliceosome

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.