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Overview

Uniprot ID	A0A287A1Y1
Protein Name	Tapasin
Gene Name	TAPBP
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
42	GRGQLSKKPAALLLR

Function

Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)

Protein Sequence

10 MKPLSLLLSV 20 VALGLASTVS 30 AGPAVIECWF 40 VEDAGRGQLS 50 KKPAALLLRQ 60 GPGSPPPRPD 70 LEPELYLKVH 80 DPAGALLAAF 90 RQYPRDAPAP 100 RCEMSHYIPL 110 PASPDWVSGL 120 TPEQRCPRAL 130 DGKWLMVSMS 140 SPVLSLSSFL 150 QPQSEPQLEP 160 ALITMATAVL 170 TVITHTPAPR 180 IRLGQDALLD 190 LSFAYVPPTS 200 KAAISLAPGP 210 PPFGLEWRRQ 220 HLGKGHLLLA 230 ATPGLSGQVP 240 AAREGAVAFA 250 AWDDDEPWGP 260 WTGNGSFWLP 270 AVQPFQEGTY 280 LATVHLPYLQ 290 GQVAMDLAVQ 300 KSPKVSLTPA 310 PLVWAAPGEA 320 PPELLCLVSH 330 FYPSEGLEVE 340 WELRGGPQGR 350 FQKAEGQSWH 360 SALSHHADGS 370 VSLSAHLQLP 380 PVTTEQHGAR 390 YACRVHHPSL 400 PALGRRSEIT 410 LQVAGLSGPS 420 LEDGVGLFLS 430 AFLLLGLIKA 440 LGWAAAHLAA 450 SRDSTQKVTV 460 LLPHLSLLVV 470 SPPPTPHSRA 480 RPQAWWASQG 490 LGIHTDLSNP 500 ATKNILHLLP WV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0030670	phagocytic vesicle membrane
Molecular Function	GO:0042605	peptide antigen binding
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.