Search Results
Overview
| Uniprot ID | A0A287A275 |
|---|---|
| Protein Name | Tubulin beta chain |
| Gene Name | TUBB4B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 78 | YNEATGGKYVPRAVL |
Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Protein Sequence
10
SYRPSAAAAV
20
ASAPAVAAAA
30
MREIVHLQAG
40
QCGNQIGAKF
50
WEVISDEHGI
60
DPTGTYHGDS
70
DLQLERINVY
80
YNEATGGKYV
90
PRAVLVDLEP
100
GTMDSVRSGP
110
FGQIFRPDNF
120
VFGQSGAGNN
130
WAKGHYTEGA
140
ELVDSVLDVV
150
RKEAESCDCL
160
QGFQLTHSLG
170
GGTGSGMGTL
180
LISKIREEYP
190
DRIMNTFSVV
200
PSPKVSDTVV
210
EPYNATLSVH
220
QLVENTDETY
230
CIDNEALYDI
240
CFRTLKLTTP
250
TYGDLNHLVS
260
ATMSGVTTCL
270
RFPGQLNADL
280
RKLAVNMVPF
290
PRLHFFMPGF
300
APLTSRGSQQ
310
YRALTVPELT
320
QQMFDAKNMM
330
AACDPRHGRY
340
LTVAAVFRGR
350
MSMKEVDEQM
360
LNVQNKNSSY
370
FVEWIPNNVK
380
TAVCDIPPRG
390
LKMSATFIGN
400
STAIQELFKR
410
ISEQFTAMFR
420
RKAFLHWYTG
430
EGMDEMEFTE
440
AESNMNDLVS
450
EYQQYQDATA
460
EEEGEFEEEA
EEEVA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005874 | microtubule |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Biological Process | GO:0007017 | microtubule-based process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.