Search Results
Overview
| Uniprot ID | A0A287A2F9 |
|---|---|
| Protein Name | Transcription elongation factor |
| Gene Name | TCEA1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 19 | MDKMVQKKNAAGALD |
| 269 | TCGKCKKKNCTYTQV |
Function
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus
Protein Sequence
10
MDDEVVRIAK
20
KMDKMVQKKN
30
AAGALDLLKE
40
LKNIPMTLEL
50
LQSTRIGMSV
60
NAIRKQSTDE
70
EVTSLAKSLI
80
KSWKKLLDGP
90
STDKDSEEKK
100
KDTAITSQNS
110
PEAREESSSS
120
GHGSSRKDEP
130
NARDTYVSSF
140
PRAPSTSDSV
150
RLKCREMLAA
160
ALRTGEDYIA
170
IGADEEELGS
180
QIEEAIYQEI
190
RNTDMKYKNR
200
VRSRISNLKD
210
AKNPNLRKNV
220
LCGNIPPDLF
230
ARMTAEEMAS
240
DELKEMRKNL
250
TKEAIREHQM
260
AKTGGTQTDL
270
FTCGKCKKKN
280
CTYTQVQTRS
290
ADEPMTTFVV
300
CNECGNRWKV
310
RHFLGFPFPP
320
FAWGGFCSGL
330
GQPGPSACVR
340
ACMRAPTARC
350
WGERGRRVLG
360
HTVCCPAGNE
AC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005669 | transcription factor TFIID complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003711 | transcription elongation factor activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006368 | transcription elongation by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.