Search Results
Overview
| Uniprot ID | A0A287A4P3 |
|---|---|
| Protein Name | Polymerase delta-interacting protein 3 |
| Gene Name | POLDIP3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 147 | TPALKLTKTIQVPQQ |
| 291 | VAEVVFVKKDDAITA |
Function
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex
Protein Sequence
10
MADISLDELI
20
RKRGAAAKGR
30
LNARPGVGGI
40
RSRVGIQQSL
50
LSQPARTATF
60
QQRFDARQKI
70
GLSDARLKLG
80
VKDAREKLLQ
90
KDARFRIKGK
100
VQDAREMLNS
110
RKQQSTVPQK
120
PRQVADAREK
130
ISLKRNSPAA
140
FMSPPIGTVT
150
PALKLTKTIQ
160
VPQQKAMAPV
170
HAHPAGMRIN
180
VVNNHQAKQA
190
GLSSSKLSMS
200
KALPLTKVVQ
210
NDAYTAPALP
220
SSVRTKALTN
230
MSRTLVNKEE
240
PPKELPPAEP
250
VLSPLEGTKM
260
TVNNLHPRVT
270
EEDIVELFCV
280
CGALKRARLV
290
HPGVAEVVFV
300
KKDDAITAYK
310
KYNNRCLDGQ
320
PMKCNLHMNG
330
NVITSDQPIL
340
LRLSDSPSVK
350
KESELPRRVN
360
SAGSSNPPAE
370
VDPDTILKAL
380
FKSSGASVTT
QPTEFKIKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0016973 | poly(A)+ mRNA export from nucleus |
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.