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Overview

Uniprot IDA0A287A682
Protein NameClathrin light chain
Gene NameCLTA
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
217 RLCDFNPKSSKQAKD

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

Protein Sequence

10 MADLDPFGAP 20 AGPSLGNGVA 30 GEEDPAAAFL 40 AQQESEIAGI 50 ENDEAFAILD 60 GGAPGPQPHG 70 EPPGGPDAVD 80 GVMNGEYYQE 90 SNGPTDSYAA 100 ISQVDRLQSE 110 PESIRKWREE 120 QTERLEALDA 130 NSRKQEAEWK 140 EKAIKELEEW 150 YARQDEQLQK 160 TKANNRVADE 170 AFYKQPFADV 180 IGYVTNINHP 190 CYSLEQAAEE 200 AFVNDIEESS 210 PGTEWERVAR 220 LCDFNPKSSK 230 QAKDVSRMRS 240 VLISLKQAPL VH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030132 clathrin coat of coated pit
Cellular Component GO:0030130 clathrin coat of trans-Golgi network vesicle
Cellular Component GO:0071439 clathrin complex
Cellular Component GO:0030125 clathrin vesicle coat
Cellular Component GO:0005768 endosome
Cellular Component GO:0005764 lysosome
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0030672 synaptic vesicle membrane
Molecular Function GO:0032050 clathrin heavy chain binding
Molecular Function GO:0005198 structural molecule activity
Biological Process GO:0048268 clathrin coat assembly
Biological Process GO:0072583 clathrin-dependent endocytosis
Biological Process GO:0006886 intracellular protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.