Search Results
Overview
| Uniprot ID | A0A287A690 |
|---|---|
| Protein Name | Peroxiredoxin-2 |
| Gene Name | PRDX2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 29 | NGAFKEVKLSDYKGK |
| 34 | EVKLSDYKGKYLVLF |
| 92 | AWINTPRKEGGLGPL |
Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)
Protein Sequence
10
MASGNAHIGK
20
PAPEFQATAV
30
VNGAFKEVKL
40
SDYKGKYLVL
50
FFYPLDFTFV
60
CPTEIIAFSD
70
RAEEFHQLGC
80
EVLGVSVDSQ
90
FTHLAWINTP
100
RKEGGLGPLK
110
IPLLADVTRN
120
LSLDYGVLKE
130
DEGIAYRGLF
140
IIDGKGVLRQ
150
ITVNDLPVGR
160
SVDEALRLVQ
170
AFQYTDEHGE
180
VCPAGWKPGS
190
DTIKPNVDDS
200
KEYFSICAPP
210
SVPCTDPGPS
220
QAPLWELVNG
230
DPLSWSDIAG
YRPFGDQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0140824 | thioredoxin-dependent peroxiredoxin activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.