Search Results
Overview
| Uniprot ID | A0A287A6C5 |
|---|---|
| Protein Name | Origin recognition complex subunit 2 |
| Gene Name | ORC2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 119 | ELAKTPRKSVSVNLK |
| 155 | VQLKSSDKSEFLSTA |
| 216 | QKTQAQNKVVSAPVC |
| 224 | VVSAPVCKETPSKKM |
| 47 | AQLLVNTKKIIKKPE |
Function
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication
Protein Sequence
10
MSKLELKENK
20
MLEVQFVGDD
30
DVLNHILDRE
40
GGAKIKKERA
50
QLLVNTKKII
60
KKPEYDVEED
70
DQEVLKDQNY
80
VEVLGRDVQE
90
SLKNGSATDG
100
GNKVYSFQNR
110
KHPEKMAKLA
120
SELAKTPRKS
130
VSVNLKSDPE
140
VMTDIPQCSK
150
GHSASDTVQL
160
KSSDKSEFLS
170
TAPRGLRKRL
180
IVPQSHSDSE
190
SEYSASNSEE
200
DEGLAQECEE
210
DTNEVILSQK
220
TQAQNKVVSA
230
PVCKETPSKK
240
MKRDKTSELV
250
EEYFEAHSSS
260
KVLTSDRTLQ
270
KLKRAKLDQQ
280
TLRNLLSKVS
290
PSFSAELKQL
300
NQQYEQLFHK
310
WMLQLHLGFN
320
IVLYGLGSKR
330
DLLERFRTAM
340
LQDCIHVVIN
350
GFFPGISVKS
360
ILNSITEEVL
370
DHMGTFRSVL
380
DQLDWIINKF
390
KEVWDHAKQS
400
LYNWLWYETT
410
TYSPYTEETS
420
YENSLLVKQS
430
GSLPLSSLTH
440
VLRSLTPNAR
450
GIFRLLMKYQ
460
LENQDNPSYT
470
GLPFQDFYQQ
480
CREAFLVNSD
490
LTLRAQLTEF
500
RDHKLLRTKK
510
GGDGVEYLLI
520
PVDNGTLTDF
LAKEEEEV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005664 | nuclear origin of replication recognition complex |
| Molecular Function | GO:0003688 | DNA replication origin binding |
| Biological Process | GO:0006260 | DNA replication |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.