Search Results
Overview
| Uniprot ID | A0A287A710 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | NFIC |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 73 | RLLAKLRKDIRPECR |
| 90 | FVLAITGKKAPGCVL |
| 91 | VLAITGKKAPGCVLS |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
MDEFHPFIEA
20
LLPHVRAFAY
30
TWFNLQARKR
40
KYFKKHEKRM
50
SKDEERAVKD
60
ELLGEKAEVK
70
QKWASRLLAK
80
LRKDIRPECR
90
EDFVLAITGK
100
KAPGCVLSNP
110
DQKGKMRRID
120
CLRQADKVWR
130
LDLVMVILFK
140
GIPLESTDGE
150
RLVKAAQCGH
160
PVLCVQPHHI
170
GVAVKELDLY
180
LAYFVRERDA
190
EQSGSPRAGM
200
GSDQEDSKPI
210
TLDTTDFQES
220
FVTSGVFSVT
230
ELIQVSRTPV
240
VTGTGPNFSL
250
GELQGHLAYD
260
LNPASTGMRR
270
TLPSTSSSGS
280
KRHKSGSMEE
290
DVDTSPGGDY
300
YTSPSSPTSS
310
NRNWTEDMEG
320
GISSPVKKTE
330
MDKSPFNSPS
340
PQDSPRLSSF
350
TQHHRPVIAV
360
HSGIARSPHP
370
SSALHFPTTS
380
ILPQTASTYF
390
PHTAIRYPPH
400
LNPQDPLKDL
410
VSLACDPASQ
420
QPGPLNGSGQ
430
LKMSSHCLSA
440
QMLAPPPPGL
450
PRLALPPATK
460
PTSEGGSSSP
470
TSPSYSTPGT
480
SPANRSFVGL
490
GPRDPTGIYQ
AQSWYLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.