Search Results
Overview
| Uniprot ID | A0A287A7E4 |
|---|---|
| Protein Name | L antigen family member 3 |
| Gene Name | LAGE3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 52 | GDPASAAKRPRSRAH |
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex
Protein Sequence
10
MQAADAAAGA
20
SGAAGGSEGP
30
GRRGAPAAAG
40
VPPVAPAQRT
50
SEEGGDPASA
60
AKRPRSRAHV
70
FALSVPFPSS
80
WEAEIARGSL
90
APDAEPHRGA
100
VGKELTVSGS
110
DLAVHWRADD
120
SRLLRISIVN
130
FLDQLSLVIR
140
TMQRFGPPVS
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0008033 | tRNA processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.