Search Results

Overview

Uniprot ID	A0A287A9Z8
Protein Name	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
Gene Name	PPP2R5D
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
114	SKNRELQKLPALKDS
133	REELFIQKLRQCCVL
483	DDCTQQYKAEKQKGR
527	EKVLLRRKSELPQDV
538	PQDVYTIKALEAHKR
83	PPPTQLSKIKYSGGP
85	PTQLSKIKYSGGPQI

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment

Protein Sequence

10 MRPRPLPSPA 20 SANSTSILSL 30 QEPPKLAKST 40 AKPSSSSKDG 50 AGESAEEAQP 60 QPQPQPQPPP 70 QPQPPSSNKR 80 PSNSTPPPTQ 90 LSKIKYSGGP 100 QIVKKERRQS 110 SSRFNLSKNR 120 ELQKLPALKD 130 SPTQEREELF 140 IQKLRQCCVL 150 FDFVSDPLSD 160 LKFKEVKRAG 170 LNEMVEYITH 180 SRDVVTEAIY 190 PEAVTMFSVN 200 LFRTLPPSSN 210 PTGAEFDPEE 220 DEPTLEAAWP 230 HLQLVYEFFL 240 RFLESPDFQP 250 NIAKKYIDQK 260 FVLALLDLFD 270 SEDPRERDFL 280 KTILHRIYGK 290 FLGLRAYIRR 300 QINHIFYRFI 310 YETEHHNGIA 320 ELLEILGSII 330 NGFALPLKEE 340 HKMFLIRVLL 350 PLHKVKSLSV 360 YHPQVIVGLL 370 KFWPKTHSPK 380 EVMFLNELEE 390 ILDVIEPSEF 400 SKVMEPLFRQ 410 LAKCVSSPHF 420 QVAERALYYW 430 NNEYIMSLIS 440 DNAARVLPIM 450 FPALYRNSKS 460 HWNKTIHGLI 470 YNALKLFMEM 480 NQKLFDDCTQ 490 QYKAEKQKGR 500 FRMKEREEMW 510 QKIEELARLN 520 PQMLKDIKKE 530 KVLLRRKSEL 540 PQDVYTIKAL 550 EAHKRAEEFL TASQEAL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005634	nucleus
Cellular Component	GO:0000159	protein phosphatase type 2A complex
Molecular Function	GO:0019888	protein phosphatase regulator activity
Biological Process	GO:0007165	signal transduction

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.