Search Results

Overview

Uniprot IDA0A287AAH4
Protein NameNa(+)/H(+) exchange regulatory cofactor NHE-RF
Gene NameNHERF1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
247 RETDEFFKKCKVIPS

Function

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression

Protein Sequence

10 MSADSAAGAP 20 LPRLCCLEKG 30 PNGYGFHLHG 40 EKGKVGQFIR 50 LVEPGSPAEK 60 SGLLAGDRLV 70 EVNGENVEKE 80 THQQVVSRIR 90 AALNAVRLLV 100 VDPETDERLQ 110 KLGVQVREEM 120 LRAQEGPGQA 130 EPPAATEAQG 140 ADSENEPPAA 150 TPEPHEAEKS 160 RQEPRELRPR 170 LCAMKKGPNG 180 YGFNLHSDKS 190 KPGQFIRAVD 200 PDSPAEASGL 210 RAQDRIVEVN 220 GVCVEGKQHG 230 DVVSAIKAGG 240 DEAKLLVVDR 250 ETDEFFKKCK 260 VIPSQEHLSG 270 PLPEPFTNGE 280 IQKLNSQDSP 290 KKEDTAASST 300 SSSSDPVLDF 310 NISLAVAKER 320 AHQKRSSKRA 330 PQMDWSKKNE LFSNL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0012505 endomembrane system
Cellular Component GO:0030175 filopodium
Cellular Component GO:0005902 microvillus
Cellular Component GO:0001726 ruffle
Molecular Function GO:0060090 molecular adaptor activity
Biological Process GO:0016055 Wnt signaling pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.