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Overview

Uniprot ID	A0A287ABG1
Protein Name	Far upstream element-binding protein 1
Gene Name	FUBP1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
125	IQQESGCKIQIAPDS
235	RITGDPYKVQQAKEM
386	KTGLIIGKGGETIKS

Function

Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription

Protein Sequence

10 MADYSTVPPP 20 SSGSAGGGGG 30 GGGGGGVNDA 40 FKDALQRARQ 50 IAAKIGGDAG 60 TSLNSNDYGY 70 GGQKRPLEDG 80 DQPDAKKVAP 90 QNDCKYLFNR 100 SVMTEEYKVP 110 DGMVGFIIGR 120 GGEQISRIQQ 130 ESGCKIQIAP 140 DSGGLPERSC 150 MLTGTPESVQ 160 SAKRLLDQIV 170 EKGRPAPGFH 180 HGDGPGNAVQ 190 EIMIPASKAG 200 LVIGKGGETI 210 KQLQERAGVK 220 MVMIQDGPQN 230 TGADKPLRIT 240 GDPYKVQQAK 250 EMVLELIRDQ 260 GGFREVRNEY 270 GSRIGGNEGI 280 DVPIPRFAVG 290 IVIGRNGEMI 300 KKIQNDAGVR 310 IQFKPDDGTT 320 PDRIAQITGP 330 PDRCQHAAEI 340 ITDLLRSVQA 350 GNPGGPGPGG 360 RGRGRGQGNW 370 NMGPPGGLQE 380 FNFIVPTGKT 390 GLIIGKGGET 400 IKSISQQSGA 410 RIELQRNPPP 420 NADPNMKLFT 430 IRGTPQQIDY 440 ARQLIEEKIG 450 GPVNPLGPPV 460 PHGPHGVPGP 470 HGPPGPPGPG 480 TPMGPYNPAP 490 YNPGPPGPAP 500 HGPPAPYAPQ 510 GWGNAYPHWQ 520 QQAPPDPAKT 530 GTDPNSAAWA 540 AYYAHYYQQQ 550 AQPPPAAPAG 560 APTTTQTNGQ 570 GDQQNPAPAG 580 QVDYTKAWEE 590 YYKKMGQQGQ 600 TQDYSKAWEE 610 YYKKQGQAVP 620 APTGAPPGGQ 630 PDYSAAWAEY 640 YRQQAAYYAQ 650 TSPQGMPQHP PAPQV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0003677	DNA binding
Molecular Function	GO:0003723	RNA binding
Biological Process	GO:0006351	DNA-templated transcription
Biological Process	GO:0006355	regulation of DNA-templated transcription

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.