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Overview

Uniprot ID	A0A287ACN4
Protein Name	Nuclear pore complex protein Nup93
Gene Name	NUP93
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
387	RNNTDPYKRAVYCII
538	LLMLYTRKFESTDPR
606	DKFTSDTKPIINKVA
718	FDIIDRLKLVPLNQE
764	FTQFKRLKGTSPSSA

Function

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling

Protein Sequence

10 MDTDGFGELL 20 QQAEQLAAET 30 EGISELPHVE 40 RNLQEIQQAG 50 ERLRSRTLTR 60 TSQETADVKA 70 SVLLGSRGLD 80 ISHISQRLES 90 LSAATTFEPL 100 EPVKDTDIQG 110 FLKNEKDNAL 120 LSAIEESRKR 130 TFGMAEEYHR 140 ESMLVEWEQV 150 KQRILHTLLA 160 SGEDALDFTQ 170 ESEPSYISDV 180 GPPGRSSLDS 190 IEMAYARQIY 200 IYNEKIVNGH 210 LQPNLVDLCA 220 SVAELDDKNI 230 SDMWAMVKQM 240 TDVLLAPATD 250 ALKSRNSVEV 260 RMEFVRQALG 270 YLEQSYKNYT 280 LVTVFGNLHQ 290 AQLGGVPGTY 300 QLVRSFLNIK 310 LPAPLPGLQD 320 GEVEGHPVWA 330 LIYYCMRCGD 340 LLAASQVVNR 350 AQHQLGEFKT 360 WFQEYMNSKD 370 RRLSPATENK 380 LRLHYRRALR 390 NNTDPYKRAV 400 YCIIGRCDVT 410 DNQSEVADKT 420 EDYLWLKLNQ 430 VCFDDDGTSS 440 PQDRLTLSQF 450 QKQLLEDYGE 460 SHFTVNQQPF 470 LYFQVLFLTA 480 QFEAAIAFLF 490 RMERLRCHAV 500 HVALVLFELK 510 LLLKSSGQSA 520 QLLSHEPGDP 530 PCMRRLNFVR 540 LLMLYTRKFE 550 STDPREALQY 560 FYFLRDEKDS 570 QGENMFLRCV 580 SELVVESREF 590 DMILGKLEND 600 GSRKPGVIDK 610 FTSDTKPIIN 620 KVASVAENKG 630 LFEEAAKLYD 640 LAKNADKVLE 650 LMNKLLSPVV 660 PQISAPQSNK 670 ERLKNMALSI 680 AERYRAQGIS 690 ANKFVDSTFY 700 LLLDLITFFD 710 EYHSGHIDRA 720 FDIIDRLKLV 730 PLNQESVEER 740 VAAFRNFSDE 750 IRHNLSEVLL 760 ATMNILFTQF 770 KRLKGTSPSS 780 ASRPQRVIED 790 RDSQLRSQAR ALITLLG

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0031965	nuclear membrane
Cellular Component	GO:0005643	nuclear pore
Molecular Function	GO:0017056	structural constituent of nuclear pore
Biological Process	GO:0051028	mRNA transport
Biological Process	GO:0015031	protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.