Search Results
Overview
| Uniprot ID | A0A287ACV7 |
|---|---|
| Protein Name | Peroxiredoxin-like 2A |
| Gene Name | PRXL2A |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 107 | AVVKEQVKNEVKDFQ |
| 127 | EIFLDEEKKFYGPQR |
| 190 | ILLEHREKEFGDKVN |
| 56 | EPKTFKAKALWEKTG |
| 88 | AADLSSLKPRLDELG |
Function
Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway
Protein Sequence
10
MGMWSIGAGA
20
IGAAALALLL
30
ANTDIFLPKP
40
QRATLDYLED
50
IDLKTLEKEP
60
KTFKAKALWE
70
KTGAVIMAVR
80
RPGCFLCREE
90
AADLSSLKPR
100
LDELGVPLYA
110
VVKEQVKNEV
120
KDFQPYFKGE
130
IFLDEEKKFY
140
GPQRRKMMFM
150
GFVRLGVWYN
160
FFRARSGGFS
170
GNLEGEGFVL
180
GGVFVVGPGK
190
QGILLEHREK
200
EFGDKVNPVS
210
VLEAVRKIKP
HTSASEKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0016209 | antioxidant activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.