Search Results
Overview
| Uniprot ID | A0A287ACY0 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | NFIC |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 104 | RLLAKLRKDIRPECR |
| 121 | FVLAITGKKAPGCVL |
| 122 | VLAITGKKAPGCVLS |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
MEVPGPLVSS
20
KPGETSVKWQ
30
LCYDMTAKMW
40
WMDEFHPFIE
50
ALLPHVRAFA
60
YTWFNLQARK
70
RKYFKKHEKR
80
MSKDEERAVK
90
DELLGEKAEV
100
KQKWASRLLA
110
KLRKDIRPEC
120
REDFVLAITG
130
KKAPGCVLSN
140
PDQKGKMRRI
150
DCLRQADKVW
160
RLDLVMVILF
170
KGIPLESTDG
180
ERLVKAAQCG
190
HPVLCVQPHH
200
IGVAVKELDL
210
YLAYFVRERD
220
AEQSGSPRAG
230
MGSDQEDSKP
240
ITLDTTDFQE
250
SFVTSGVFSV
260
TELIQVSRTP
270
VVTGTGPNFS
280
LGELQGHLAY
290
DLNPASTGMR
300
RTLPSTSSSG
310
SKRHKSGSME
320
EDVDTSPGGD
330
YYTSPSSPTS
340
SNRNWTEDME
350
GGISSPVKKT
360
EMDKSPFNSP
370
SPQDSPRLSS
380
FTQHHRPVIA
390
VHSGIARSPH
400
PSSALHFPTT
410
SILPQTASTY
420
FPHTAIRYPP
430
HLNPQDPLKD
440
LVSLACDPAS
450
QQPGPLNGSG
460
QLKMSSHCLS
470
AQMLAPPPPG
480
LPRLALPPAT
490
KPTSEGGSSS
500
PTSPSYSTPG
510
TSPANRSFVG
520
LGPRDPTGIY
QAQSWYLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.