Search Results
Overview
| Uniprot ID | A0A287AD92 |
|---|---|
| Protein Name | GrpE protein homolog |
| Gene Name | - |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 214 | PALVGVVKEA***** |
| 93 | NFRQRSQKLVEEAKL |
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins
Protein Sequence
10
MAAPCVRVAR
20
RSLSALALSL
30
RPSPRLLCTA
40
TKQKNNGQNL
50
EEDAGQNEQK
60
TDLPSTEKTL
70
MEEKVKLEEQ
80
LKEAMEKYKR
90
AADTENFRQR
100
SQKLVEEAKL
110
YGIQGFCKDL
120
LEVADILEKA
130
TQSVPKEEIR
140
DDNPHLKNLY
150
EGLLMTEAQI
160
QKVFTKHGLL
170
RLDPLGAKFD
180
PYEHEALFHT
190
PVEGKEPGTV
200
ALVNKVGYKL
210
HGRTLRPALV
GVVKEA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0001405 | PAM complex, Tim23 associated import motor |
| Molecular Function | GO:0000774 | adenyl-nucleotide exchange factor activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0030150 | protein import into mitochondrial matrix |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.