Search Results
Overview
| Uniprot ID | A0A287AEC0 |
|---|---|
| Protein Name | eIF5-mimic protein 1 |
| Gene Name | BZW2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 310 | NAVEWNKKEELVAEQ |
Function
Translation initiation regulator which represses non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function. Increases the accuracy of translation initiation by impeding EIF5-dependent translation from non-AUG codons by competing with it for interaction with EIF2S2 within the 43S pre-initiation complex (PIC) in an EIF3C-binding dependent manner
Protein Sequence
10
MNKHQKPVLT
20
GQRFKTRKRD
30
EKEKFEPTVF
40
RDTLVQGLNE
50
AGDDLEAVAK
60
FLDSTGSRLD
70
YRRYADTLFD
80
ILVAGSMLAP
90
GGTRIDDGDK
100
TKMTNHCVFS
110
ANEDHETIRN
120
YAQVFNKLIR
130
RYKYLEKAFE
140
DEMKKLLLFL
150
KAFSETEQTK
160
LAMLSGILLG
170
NGTLPATILT
180
SLFTDSLVKE
190
GIAASFAVKL
200
FKAWMAEKDA
210
NSVTSSLRKA
220
NLDKRLLELF
230
PVNRQSVDHF
240
AKYFTDAGLK
250
ELSDFLRVQQ
260
SLGTRKELQK
270
ELQERLSQEC
280
PIKEVVLYVK
290
EEMKRNDLPE
300
TAVIGLLWTC
310
IMNAVEWNKK
320
EELVAEQALK
330
HLKQYAPLLA
340
VFSSQGQSEL
350
ILLQKVQEYC
360
YDNIHFMKAF
370
QKIVVLFYKG
380
VYGCMLFCHC
MSLCFVEAL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.