Search Results
Overview
| Uniprot ID | A0A287AEH0 |
|---|---|
| Protein Name | 26S proteasome non-ATPase regulatory subunit 7 |
| Gene Name | PSMD7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 180 | EHLLRDIKDTTVGTL |
| 204 | GLKGLNSKLLDIRSY |
| 214 | DIRSYLEKVATGKLP |
| 279 | LHNLINNKIANRDAE |
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair
Protein Sequence
10
MPELAVQKVV
20
VHPLVLLSVV
30
DHFNRIGKVG
40
NQKRVVGVLL
50
GSWQKKVLDV
60
SNSFAVPFDE
70
DDKDDSVWFL
80
DHDYLENMYG
90
MFKKVNARER
100
IVGWYHTGPK
110
LHKNDIAINE
120
LMKRYCPNSV
130
LVIIDVKPKD
140
LGLPTEAYIS
150
VEEVHDDGTP
160
TSKTFEHVTS
170
EIGAEEAEEV
180
GVEHLLRDIK
190
DTTVGTLSQR
200
ITNQVHGLKG
210
LNSKLLDIRS
220
YLEKVATGKL
230
PINHQIIYQL
240
QDVFNLLPDV
250
SLQEFVKAFY
260
LKTNDQMVVV
270
YLASLIRSVV
280
ALHNLINNKI
290
ANRDAEKKEG
300
QEKEDSKKDR
310
KDDKEKEKDK
320
EKSDVKKEEK
KEKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000502 | proteasome complex |
| Cellular Component | GO:0005838 | proteasome regulatory particle |
| Molecular Function | GO:0008237 | metallopeptidase activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.