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Overview

Uniprot IDA0A287AEQ0
Protein NameProthymosin alpha
Gene NamePTMA
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
15 TSSEITTKDLKEKKE

Function

Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections

Protein Sequence

10 MSDAAVDTSS 20 EITTKDLKEK 30 KEVVEEAENG 40 REAPANGNAN 50 EENGEQEADN 60 EVDEEEEEGG 70 EEEEEEEEGD 80 GEEEDGDEDE 90 EAEAATGKRA 100 AEDDEKNPKR 110 GHLRVESRLP 120 ARPPRAAPPA 130 DDVRSPPPHQ 140 NHNVNLPQGR 150 KERTKTSKAL 160 LFFLKYFKKE 170 NLFVFFIYIL YFCTYC

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Molecular Function GO:0042393 histone binding
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.