Search Results
Overview
| Uniprot ID | A0A287AH85 |
|---|---|
| Protein Name | Adenylate kinase 2, mitochondrial |
| Gene Name | AK2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 30 | LGPPGAGKGTQAPRL |
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis
Protein Sequence
10
MAPNVTASEP
20
AQEGPKGIRA
30
VLLGPPGAGK
40
GTQAPRLAEN
50
FCVCHLATGD
60
MLRAMVASGS
70
ELGKKLKATM
80
DAGKLVSDEM
90
VVELIEKNLE
100
TPPCKNGFLL
110
DGFPRTVRQA
120
EMLDDLMEKR
130
KEKLDSVIEF
140
SIPDALLIRR
150
ITGRLIHPKS
160
GRSYHEEFNP
170
PKEPMKDDIT
180
GEPLIRRSDD
190
NEKALKIRLE
200
AYHTQTTPLV
210
EYYSKRGIHS
220
AIDASQTPDV
230
VFASILAAFS
KATS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005758 | mitochondrial intermembrane space |
| Molecular Function | GO:0004017 | AMP kinase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Biological Process | GO:0006172 | ADP biosynthetic process |
| Biological Process | GO:0046033 | AMP metabolic process |
| Biological Process | GO:0046034 | ATP metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.