Search Results
Overview
| Uniprot ID | A0A287AHF2 |
|---|---|
| Protein Name | N-alpha-acetyltransferase 30 |
| Gene Name | NAA30 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 65 | SEATAATKGRPCLRC |
Function
Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate
Protein Sequence
10
MAEVPPGPSS
20
LLPPPAPPAS
30
AAAEPRCPFP
40
AGAALACCSE
50
DEEDDEEHEG
60
GGRSPAGSEA
70
TAATKGRPCL
80
RCPQPPQEQL
90
QLNGLINPEL
100
RHLRAATSLK
110
TKVLSAAEAA
120
TITATPDGGP
130
RVTATKGAGV
140
HSGEGPPHCL
150
PNNARTALPS
160
PAEAAAAASD
170
PAAARNGLAE
180
GTEQEEEEDE
190
QVRLLSSSLT
200
AGCSIRSPSG
210
REVEPGEDRT
220
IRYVRYESEL
230
QMPDIMRLIT
240
KDLSEPYSIY
250
TYRYFIHNWP
260
QLCFLAMVGE
270
ECVGAIVCKL
280
DMHKKMFRRG
290
YIAMLAVDSK
300
YRRNGIGTNL
310
VKKAIYAMVE
320
GDCDEVVLET
330
EITNKSALKL
340
YENLGFVRDK
350
RLFRYYLNGV
360
DALRLKLWLR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0120518 | protein N-terminal-methionine acetyltransferase activity |
| Molecular Function | GO:0004596 | protein-N-terminal amino-acid acetyltransferase activity |
| Biological Process | GO:0050821 | protein stabilization |
| Cellular Component | GO:0031417 | NatC complex |
| Cellular Component | GO:0005634 | nucleus |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.