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Overview

Uniprot IDA0A287AHM8
Protein NameTorsin-1A-interacting protein 1
Gene NameTOR1AIP1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
576 VQPENDLKRGICL**

Function

Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina

Protein Sequence

10 MGGVRHAQGP 20 LREGRSRLAP 30 QNGGGSDAPA 40 YGTPTPPRHS 50 RREVRFSEEP 60 PEVYGDFEPR 70 AAKEKVPVGR 80 QIPLEEFRPD 90 SAKEEVRESA 100 YYLRSRRQRQ 110 PRLPEAEEMK 120 TRRGTRLQQQ 130 QQQPHSQPPP 140 LQSSPVTTRR 150 GLRDSHSSEE 160 DETPSQTVLS 170 QTVSKKTIMR 180 TQETPVVSED 190 PVISLRRPPL 200 RSSRSEATSV 210 QQKVNFSEEG 220 ETEENDQDSS 230 DSDVTTVKFR 240 SRDSVASGGN 250 TTLCTYDSSL 260 RNCIFSSSGD 270 FITLDKQPLV 280 LSSGYQKNPQ 290 QWVEQTTRIR 300 TRMQSKLINL 310 YDSVQKPELG 320 NQSPSTSSQQ 330 VTGQAKTTSF 340 FKIKWWWFPV 350 VIVALAIGNF 360 WFSRTSEAET 370 TAVQEFQNQM 380 KQLMNKYQGQ 390 DEKLWRRSQT 400 FLEKHLNSSQ 410 PRPQPAILLL 420 TAARDAEEAL 430 KCLSEQIADA 440 YSSFRSVPAI 450 RIDGAGKATQ 460 DSDIVKQEVD 470 EELSNGFKNG 480 QNAAVVHRFE 490 SLPAGSTLIF 500 YKYCDHENAA 510 FKDVALVLTV 520 LLEEETLGTS 530 LGLKEIEEKV 540 RDFLQVKFTN 550 SDTPDSYKHM 560 DPDKLNGLWS 570 RISHLVLPVQ 580 PENDLKRGIC L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005637 nuclear inner membrane
Molecular Function GO:0001671 ATPase activator activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.