Search Results
Overview
| Uniprot ID | A0A287AIW3 |
|---|---|
| Protein Name | Dynein light intermediate chain |
| Gene Name | DYNC1LI1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 385 | KLQSLLAKQPPTAAG |
| 63 | VSTRSRSKLPAGKNV |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes
Protein Sequence
10
MAAVGRVGSF
20
GSSPPGLVST
30
YTGGPLANEL
40
TSGNGGAATG
50
DDEDGQNLWS
60
CILSEVSTRS
70
RSKLPAGKNV
80
LLLGEDGAGK
90
TSLIRKIQGI
100
EEYKKGRGLE
110
YLYLNVHDED
120
RDDQTRCNVW
130
ILDGDPYHKG
140
LLKFSLDAIS
150
LKDTLVMLVV
160
DMSKPWTALD
170
SLQKWASVVR
180
EHIDKLKIPP
190
EEMKEMEQKL
200
IRDFQEYVEP
210
GEDFPASPQR
220
RNTVSQEDKD
230
DSVVLPLGAD
240
TLTQNLGIPV
250
LVVCTKCDAI
260
SVLEKEHDYR
270
DEHFDFIQSH
280
IRKFCLQYGA
290
ALIYTSVKEN
300
KNIDLVYKYI
310
VQKLYGFPYK
320
IPAVVVEKDA
330
VFIPAGWDND
340
KKIGILHENF
350
QTLKAEDNFE
360
DIITKPPVRK
370
FVHEKEIVAE
380
DDQVFLMKLQ
390
SLLAKQPPTA
400
AGRPVDASPR
410
VPGGSPRTPN
420
RSVSSNVASV
430
SPIPAGSKKI
440
DPNMKAGATS
450
EGVLANFFNS
460
LLSKKTGSPG
470
GPAVGGGSPG
480
GGAGGGSSGL
490
PPSAKKSGQK
500
PVLSDVHAEL
510
DRIARKPVTV
520
SSTTPTSPTE
GEAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005868 | cytoplasmic dynein complex |
| Cellular Component | GO:0030666 | endocytic vesicle membrane |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0000922 | spindle pole |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0045504 | dynein heavy chain binding |
| Molecular Function | GO:0019003 | GDP binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0061502 | early endosome to recycling endosome transport |
| Biological Process | GO:0000226 | microtubule cytoskeleton organization |
| Biological Process | GO:0007018 | microtubule-based movement |
| Biological Process | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint |
| Biological Process | GO:0060627 | regulation of vesicle-mediated transport |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.