Search Results
Overview
| Uniprot ID | A0A287AJ98 |
|---|---|
| Protein Name | Ribonucleoside-diphosphate reductase subunit M2 |
| Gene Name | RRM2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 256 | TMPCVKKKADWALRW |
| 333 | MFKHLLHKPSEQRVK |
| 340 | KPSEQRVKEIIVNAV |
| 96 | GTRVLASKTARRIFQ |
Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling
Protein Sequence
10
MALPSLPGPF
20
YWPLHQPHLQ
30
NLSPRTAKPV
40
RETFSERTCA
50
FASPAPPRVA
60
MLSVRVPLAT
70
IADPQQLQLS
80
PLKGLSLADK
90
ENTPPTLSGT
100
RVLASKTARR
110
IFQEPAEPNP
120
KLSAPSVEDE
130
PLLRENPRRF
140
VIFPIEYHDI
150
WQMYKKAEAS
160
FWTAEEVDLS
170
KDIQHWETLK
180
PEERYFISHV
190
LAFFAASDGI
200
VNENLVERFS
210
QEVQITEARC
220
FYGFQIAMEN
230
IHSEMYSLLI
240
DTYIKDSKER
250
EFLFNAIETM
260
PCVKKKADWA
270
LRWIGDKEAT
280
YGERVVAFAA
290
VEGIFFSGSF
300
ASIFWLKKRG
310
LMPGLTFSNE
320
LISRDEGLHC
330
DFACLMFKHL
340
LHKPSEQRVK
350
EIIVNAVRIE
360
QEFLTEALPV
370
KLIGMNCTLM
380
KQYIEFVADR
390
LMLELGFGKV
400
FRVENPFDFM
410
ENISLEGKTN
420
FFEKRVGEYQ
430
RMGVMSSPTE
NSFTLDADF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| Biological Process | GO:0009263 | deoxyribonucleotide biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.