Search Results
Overview
| Uniprot ID | A0A287AL59 |
|---|---|
| Protein Name | Ethanolamine-phosphate cytidylyltransferase |
| Gene Name | PCYT2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | RDTYEEVKQAGRYRE |
| 344 | SDPYEEPKRRGIFCQ |
Function
Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway. Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis
Protein Sequence
10
MIRNGHETAG
20
GAERPGPGGR
30
RPVRVWCDGC
40
YDMVHYGHSN
50
QLRQARAMGD
60
HLIVGVHTDE
70
EISKHKGPPV
80
FTQEERYRMV
90
QAIKWVDEVV
100
PAAPYVTTLE
110
TLDKYGCDFC
120
VHGNDITLTV
130
DGRDTYEEVK
140
QAGRYRECKR
150
TQGVSTTDLV
160
GRMLLVTKAH
170
HSSQEMPSEY
180
REYADSFGKP
190
PHPTPAGETL
200
SSGGSSQGPG
210
GRNPWTGVSQ
220
FLQTSQKIIQ
230
FASGKEPQPG
240
ETVVYVAGAF
250
DLFHIGHVDF
260
LEKVHGLAER
270
PYVIAGLHFD
280
QEVNRYKGKN
290
YPIMNLHERT
300
LSVLACRYVS
310
EVVIGAPYSV
320
TAELLDHFKV
330
DLVCHGKTEI
340
VADRDGSDPY
350
EEPKRRGIFC
360
QISSGNDLTT
370
DLIVQRIIKN
380
RLEYEARNQK
390
KEAKELAFLE
400
AMRQQEVRPE
GESDCDF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity |
| Biological Process | GO:0006646 | phosphatidylethanolamine biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.