Search Results
Overview
| Uniprot ID | A0A287ALY8 |
|---|---|
| Protein Name | Ribonucleoside-diphosphate reductase subunit M2 |
| Gene Name | RRM2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 206 | TMPCVKKKADWALRW |
| 283 | MFKHLLHKPSEQRVK |
| 290 | KPSEQRVKEIIVNAV |
| 46 | GTRVLASKTARRIFQ |
Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling
Protein Sequence
10
MLSVRVPLAT
20
IADPQQLQLS
30
PLKGLSLADK
40
ENTPPTLSGT
50
RVLASKTARR
60
IFQEPAEPNP
70
KLSAPSVEDE
80
PLLRENPRRF
90
VIFPIEYHDI
100
WQMYKKAEAS
110
FWTAEEVDLS
120
KDIQHWETLK
130
PEERYFISHV
140
LAFFAASDGI
150
VNENLVERFS
160
QEVQITEARC
170
FYGFQIAMEN
180
IHSEMYSLLI
190
DTYIKDSKER
200
EFLFNAIETM
210
PCVKKKADWA
220
LRWIGDKEAT
230
YGERVVAFAA
240
VEGIFFSGSF
250
ASIFWLKKRG
260
LMPGLTFSNE
270
LISRDEGLHC
280
DFACLMFKHL
290
LHKPSEQRVK
300
EIIVNAVRIE
310
QEFLTEALPV
320
KLIGMNCTLM
330
KQYIEFVADR
340
LMLELGFGKV
350
FRVENPFDFM
360
ENISLEGKTN
370
FFEKRVGEYQ
380
RMGVMSSPTE
NSFTLDADF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| Biological Process | GO:0009263 | deoxyribonucleotide biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.