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Overview

Uniprot IDA0A287AM87
Protein NameMitochondrial import inner membrane translocase subunit TIM50
Gene NameTIMM50
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
245 RVVVVDCKKEAFRLQ
66 SEGPSYAKKVALWLA

Function

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo

Protein Sequence

10 MAASAGLFLR 20 LRSGLLQGAR 30 GLCARLATAP 40 PRAPDQTAEI 50 GSRAGTKVQV 60 QGPQQQRSSE 70 GPSYAKKVAL 80 WLAGLLGAGG 90 TVSIVYIFGE 100 RHMPVHQFSY 110 PILVQQLRRT 120 YKYFKDYRQM 130 IIEPTSPCLL 140 PDPLREPYYQ 150 PPYTLVLELT 160 GVLLHPEWSL 170 ATGWRFKKRP 180 GIETLFQQLA 190 PLYEIVIFTS 200 ETGMTAFPLI 210 DSVDPHGFIS 220 YRLFRDATRY 230 MDGHHVKDIS 240 CLNRDPARVV 250 VVDCKKEAFR 260 LQPYNGVALR 270 PWDGNSDDRV 280 LLDLSAFLKT 290 IALNGVEDVR 300 TVLEHYALEE 310 DPLEAFKQRQ 320 SRLEQEEQQR 330 LAELSKSSKQ 340 NLFFGSLTSR LWPRSKQP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005744 TIM23 mitochondrial import inner membrane translocase complex
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.