Search Results
Overview
| Uniprot ID | A0A287AM88 |
|---|---|
| Protein Name | Lysyl oxidase homolog |
| Gene Name | LOXL2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 161 | VGVVCSDKRIPGFKF |
Function
Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)
Protein Sequence
10
MERRAGSCLC
20
SCLAVLALLP
30
ALSLAQYESW
40
PHYPEYFQQP
50
APEYHRPQAP
60
SDVVKIQLRL
70
AGQKRKHSEG
80
RLEVYYNGQW
90
GTVCDDDFSI
100
HAAHVVCREL
110
GYVEAKSWTA
120
SSSYGKGEGP
130
IWLDNVYCTG
140
QEATLAACSS
150
NGWGVTDCKH
160
TEDVGVVCSD
170
KRIPGFKFDN
180
SLINNIENMN
190
IQVEDIRIRA
200
ILSAYRKRTP
210
VTEGYVEVKE
220
GKTWKQICDK
230
HWTAKNSRVV
240
CGMMFAARKK
250
QRYWPFSMDC
260
TGTEAHISSC
270
KLGPQVSLDP
280
VKNVTCENGL
290
PAVVSCVPGQ
300
VFSADGPSRF
310
RKAYKPEQPL
320
VRLRGGANVG
330
EGRVEVLKNG
340
EWGTVCDDKW
350
DLVSASVVCR
360
ELGFGSAKEA
370
ITGSRLGQGI
380
GPIHLNEIQC
390
TGNEKSIIDC
400
KFNAESQGCN
410
HEEDAGVRCN
420
IPAMGFQKKL
430
RLNGGRNPYE
440
GRVEVLVERN
450
GSLVWGTVCG
460
ENWGIVEAMV
470
VCRQLGLGFA
480
SNAFQETWYW
490
HGNAHNKVVM
500
SGVKCSGTEL
510
SLAHCRHDGE
520
DVACPQGGVQ
530
YGAGVACSET
540
APDLVLNAEI
550
VQQSTYLEDR
560
PMFMLQCAME
570
ENCLAASAAQ
580
TNPTTGYRRL
590
LRFSSQIHNN
600
GQSDFRPKNG
610
RHAWIWHDCH
620
RHYHSMEVFT
630
HYDLLNLNGT
640
KVAEGHKASF
650
CLEDTECEGD
660
IQKSYECANF
670
GEQGITMGCW
680
DMYRHDIDCQ
690
WVDITDVPPG
700
DYLFQVVINP
710
NYEVAESDYT
720
NNIMKCRTRY
730
DGHRIWMYNC
740
HIGGSFSEET
750
EKKFEHFSGL
INNQLTSR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005604 | basement membrane |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0005507 | copper ion binding |
| Molecular Function | GO:0070492 | oligosaccharide binding |
| Molecular Function | GO:0004720 | protein-lysine 6-oxidase activity |
| Biological Process | GO:0030199 | collagen fibril organization |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0043542 | endothelial cell migration |
| Biological Process | GO:0001935 | endothelial cell proliferation |
| Biological Process | GO:0001837 | epithelial to mesenchymal transition |
| Biological Process | GO:0070828 | heterochromatin organization |
| Biological Process | GO:1902455 | negative regulation of stem cell population maintenance |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0032332 | positive regulation of chondrocyte differentiation |
| Biological Process | GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| Biological Process | GO:0046688 | response to copper ion |
| Biological Process | GO:0001666 | response to hypoxia |
| Biological Process | GO:0002040 | sprouting angiogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.