Search Results

Overview

Uniprot IDA0A287AMJ0
Protein NameAntiviral innate immune response receptor RIG-I
Gene NameRIGI
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
638 TRTILFVKTRALVDA
647 RALVDALKKWIKENP
782 DEAVFKEKIHQIQIR
864 GNIEKRAKIYCARPD
99 WDFQKIEKLEEYRSL

Function

No function data available.

Protein Sequence

10 MTAEQRRNLH 20 AFGDYVRKTL 30 DPTFILSYMA 40 PWFRDDEVQH 50 IQAEKNNKGP 60 TEAASLFLQF 70 LLELQEEGWF 80 RGFLDALNQA 90 GYCGLCEAIE 100 SWDFQKIEKL 110 EEYRSLLRRL 120 QPEFKTTINP 130 KDILPEIAEC 140 LISQECEEIL 150 QICSSKGLMA 160 GAEKMVECLL 170 RSDKENWPKT 180 LKLALEKEES 190 RFSELWMVDK 200 GAEDVKMKDL 210 EDDEMKTCDV 220 QIFYKEEPEN 230 QNLSQNSCSS 240 SAPHTYSPLK 250 PRKYQLELAL 260 PAQNGKNTII 270 CAPTGCGKTF 280 VSLLICEHHL 290 KKFPRGRKGK 300 VVFFAIQLPV 310 YEQQKSVFSK 320 HFERLGYKVA 330 GISGATSDTV 340 CVEQIVENND 350 IIILTPQILV 360 NCLTNGTIPS 370 LSVFTLMIFD 380 ECHNTSKQHP 390 YNVIMFNYLD 400 RKLGGSSDSL 410 PQVIGLTASV 420 GVGDAKNKAE 430 ATEYICKLCA 440 SLDTSVIATV 450 RDNLEELEEV 460 VYKPQKFFRK 470 VELRTTDRFK 480 CIISQLMMEI 490 ESLAKSIFEE 500 LGTITLGGLF 510 QIQNSNFGTQ 520 KYEQWIVKVQ 530 KECAVFQMPD 540 KDKESRICKA 550 LFSYMSHLRI 560 YNDALIINEH 570 ARMKDALDYL 580 KDFFRNIRAA 590 GFDEIEQDLT 600 QRFEEKLQEL 610 ESISIDPSNE 620 NPKLRDLCFI 630 LQEEYHLNPE 640 TRTILFVKTR 650 ALVDALKKWI 660 KENPKLSFLK 670 PSILTGRGKT 680 NQNIGMTLPA 690 QKCVLDTFRT 700 DKDNKILITT 710 SVADEGIDIA 720 QCNLVILYEY 730 VGNVIKMIQT 740 RGRGRARGSK 750 CFLLTANADL 760 IDKEKMNMYK 770 EEMMNGAILI 780 LQTWDEAVFK 790 EKIHQIQIRE 800 KIIRDNQGKP 810 EPVPDKKTKK 820 LLCKKCKAFA 830 CYTADIRMVE 840 NCHFTVVGDA 850 FRERFVSKLH 860 PKPKSFGNIE 870 KRAKIYCARP 880 DCSHDWGIYV 890 RYKAFEMPFI 900 KIESFVVEDI 910 ATGVQTVHAK 920 WKDFNFEKLS 930 FDAAEMAGGA 940 QDLGLQGMGN LE

Gene Ontology

Classification GO ID Description
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0005923 bicellular tight junction
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:1990904 ribonucleoprotein complex
Cellular Component GO:0032587 ruffle membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0003690 double-stranded DNA binding
Molecular Function GO:0003725 double-stranded RNA binding
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0038187 pattern recognition receptor activity
Molecular Function GO:0003724 RNA helicase activity
Molecular Function GO:0003727 single-stranded RNA binding
Molecular Function GO:0031625 ubiquitin protein ligase binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0140374 antiviral innate immune response
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0002753 cytoplasmic pattern recognition receptor signaling pathway
Biological Process GO:0009597 detection of virus
Biological Process GO:0010467 gene expression
Biological Process GO:0002230 positive regulation of defense response to virus by host
Biological Process GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
Biological Process GO:0032727 positive regulation of interferon-alpha production
Biological Process GO:0032728 positive regulation of interferon-beta production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0002735 positive regulation of myeloid dendritic cell cytokine production
Biological Process GO:0060760 positive regulation of response to cytokine stimulus
Biological Process GO:0032760 positive regulation of tumor necrosis factor production
Biological Process GO:0030334 regulation of cell migration
Biological Process GO:0039529 RIG-I signaling pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.