Search Results
Overview
| Uniprot ID | A0A287AMS8 |
|---|---|
| Protein Name | U4/U6 small nuclear ribonucleoprotein Prp31 |
| Gene Name | PRPF31 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 317 | AARLVAAKCTLAARV |
| 441 | ATKARISKTLQRTLQ |
| 449 | TLQRTLQKQSVVYGG |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome
Protein Sequence
10
MALVGSLALE
20
LCHAPTGLGM
30
SLADELLADL
40
EEAAEEEEGG
50
SYGEEEEEPA
60
IEDVQEETQL
70
DLSGDSVKSI
80
AKLWDSKMFA
90
EIMLKIEEYI
100
SKQADAAEVM
110
GPVEAAPEYP
120
VIVDANNLTV
130
EIENELNIIH
140
KFIRDKYSKR
150
FPELESLVPN
160
ALDYIRTVKE
170
LGNSLDKCKN
180
NENLQQILTN
190
ATIMVVSVTA
200
STTQGQQLSD
210
EELERLEEAC
220
DMALELNASK
230
HRIYEYVESR
240
MSFIAPNLSI
250
IIGASTAAKI
260
MGVAGGLTNL
270
SKMPACNIML
280
LGAQRKTLSG
290
FSSTSVLPHT
300
GYIYHSDIVQ
310
SLPPDLRRKA
320
ARLVAAKCTL
330
AARVDSFHES
340
TEGKVGYELK
350
DEIERKFDKW
360
QEPPPVKQVK
370
PLPAPLDGQR
380
KKRGGRRYRK
390
MKERLGLTEI
400
RKQANRMSFG
410
EIEEDAYQED
420
LGFSLGHLGK
430
SGSGRVRQTQ
440
VNEATKARIS
450
KTLQRTLQKQ
460
SVVYGGKSTI
470
RDRSSGTASS
480
VAFTPLQGLE
490
IVNPQAAEKK
500
VAEANQKYFS
510
SMAEFLKVKG
EKSGIMST
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015030 | Cajal body |
| Cellular Component | GO:0071339 | MLL1 complex |
| Biological Process | GO:0000244 | spliceosomal tri-snRNP complex assembly |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0097526 | spliceosomal tri-snRNP complex |
| Cellular Component | GO:0071005 | U2-type precatalytic spliceosome |
| Cellular Component | GO:0005687 | U4 snRNP |
| Cellular Component | GO:0046540 | U4/U6 x U5 tri-snRNP complex |
| Cellular Component | GO:0005690 | U4atac snRNP |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Molecular Function | GO:0070990 | snRNP binding |
| Molecular Function | GO:0030621 | U4 snRNA binding |
| Molecular Function | GO:0030622 | U4atac snRNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0071166 | ribonucleoprotein complex localization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.