Search Results

Overview

Uniprot ID	A0A287AT83
Protein Name	Eukaryotic translation initiation factor 4B
Gene Name	EIF4B
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
431	LENETSNKEEDCQSP

Function

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F

Protein Sequence

10 MAASAKKKNK 20 KGKTISLTDF 30 LAEDGGTGGG 40 STYVPKPVSW 50 ADETDDLEGD 60 VSTTWHSNDD 70 DVYRAPPIDR 80 SILPTAPRAA 90 REPNIDRSRL 100 PKSPPYTAFL 110 GNLPYDVTED 120 SIKEFFRGLN 130 ISAVRLPREP 140 SNPERLKGFG 150 YAEFEDLDSL 160 LSALSLNEES 170 LGNRRIRVDV 180 ADQAQDKDRD 190 DRSFGRDRNR 200 DSDKTDTDWR 210 ARPATDSFDD 220 YPPRRGDDSF 230 GDKYRDRYDS 240 DRYRDGYRDS 250 YRDGPRRDMD 260 RYGGRDRYDD 270 RGSRDYDRGY 280 DSRIGSGRRA 290 FGSGYRRDDD 300 YRGGGDRYED 310 RYDRRDDRSW 320 SSRDDYSRDD 330 YRRDDRGPPQ 340 RPKLNLKPRS 350 TPKEDDSSAR 360 EREVEERLQK 370 EQEKLQRQLD 380 EPKLERRPRE 390 RHPSWRSEET 400 QERERSRTGS 410 ESSQTGTSAA 420 SGRNARRRES 430 EKSLENETSN 440 KEEDCQSPTS 450 KPPKPEQPLK 460 VMPAPPPKEN 470 AWVKRSSNPP 480 ARSQSSDTEQ 490 QSPTSGGGKV 500 VPSHPSEEGP 510 ARKDENKVDG 520 VSVPKGQSGN 530 SSRGPGDGGS 540 RDHWKESDRK 550 DGRKDQDSRS 560 APEPKKAEEN 570 PASKFSSASK 580 YAALSIDGED ENEGDYTE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0003723	RNA binding
Molecular Function	GO:0003743	translation initiation factor activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.