Search Results
Overview
| Uniprot ID | A0A287AV76 |
|---|---|
| Protein Name | BAG family molecular chaperone regulator 2 |
| Gene Name | BAG2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 111 | PQQQESLKQATRIID |
| 168 | GCALEDQKKIKRRLE |
| 195 | IKLLEHSKGASKTLQ |
| 199 | EHSKGASKTLQQNTE |
| 9 | AQARISAKANEGRFC |
Function
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release
Protein Sequence
10
MAQARISAKA
20
NEGRFCRSSS
30
MADRSSRLLE
40
SLDQLELRVE
50
ALREAATAVE
60
QEKEVLLEMI
70
HSIQNSQDMR
80
QISEGEREEL
90
NLTANRLMGR
100
TLTVEVSVET
110
IRNPQQQESL
120
KQATRIIDEV
130
VSKFLDDLGN
140
AKSHLMSLYS
150
ACSSEVPAGP
160
VDQKFQSIVI
170
GCALEDQKKI
180
KRRLETLLRN
190
IENSDKAIKL
200
LEHSKGASKT
210
LQQNTESRFN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0000774 | adenyl-nucleotide exchange factor activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Biological Process | GO:0031397 | negative regulation of protein ubiquitination |
| Biological Process | GO:0045862 | positive regulation of proteolysis |
| Biological Process | GO:0050821 | protein stabilization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.