Search Results
Overview
| Uniprot ID | A0A287AVN3 |
|---|---|
| Protein Name | Dynein light intermediate chain |
| Gene Name | DYNC1LI2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 278 | YTSVKEEKNLDLLYK |
| 440 | FNSLLSKKTGSPGSP |
| 8 | MAPVGVEKKLLLGPN |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes
Protein Sequence
10
MAPVGVEKKL
20
LLGPNGPAVA
30
AAGDLTSEEE
40
EGQSLWSSIL
50
SEVSTRARSK
60
LPSGKNILVF
70
GEDGSGKTTL
80
MTKLQGAEHG
90
KKGRGLEYLY
100
LSIHDEDRDD
110
HTRCNVWILD
120
GDLYHKGLLK
130
FAVSAESLPE
140
TLVIFVADMS
150
RPWTVMESLQ
160
KWASVLREHI
170
DKMKIPPEEM
180
RELERKFMKD
190
FQDYIEPEEG
200
SQGSPQRRGP
210
LTSGPDEENV
220
ALPLGDNVLT
230
HNLGVPVLVV
240
CTKCDAVSVL
250
EKEHDYRDEH
260
FDFIQSHLRR
270
FCLQYGAALI
280
YTSVKEEKNL
290
DLLYKYIVHK
300
TYGFHFTTPA
310
LVVEKEAVFI
320
PAGWDNEKKI
330
AILHENFTTV
340
KPEDAYEDFI
350
VKPPVRKLVH
360
DKELAAEDEQ
370
VFLMKQQSLL
380
AKQPATPTRA
390
SESPARGPSG
400
SPRTQGRGGP
410
ASVPSASPGT
420
SVKKPDPNIK
430
NNAASEGVLA
440
SFFNSLLSKK
450
TGSPGSPGAG
460
GVQSTAKKSG
470
QKTVLTNVQE
480
ELDRMTRKPD
490
SMAGLLVENG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005868 | cytoplasmic dynein complex |
| Cellular Component | GO:0005874 | microtubule |
| Molecular Function | GO:0005524 | ATP binding |
| Biological Process | GO:0007018 | microtubule-based movement |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.