Search Results

Overview

Uniprot IDA0A287AX76
Protein NameSynapse-associated protein 1
Gene NameSYAP1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
197 MRFALVPKLVKEEVF
260 KTPPVVIKSQLKTQE

Function

Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation

Protein Sequence

10 MFRGLSSWFG 20 LEQPAPGGRQ 30 SEGDGQPKGD 40 APPEQRSEAV 50 AETAEGEPQQ 60 AGDQELLHQA 70 KGLGNYLFNF 80 ATAATKKITE 90 SVAETAQTIK 100 KSVEEGKIDD 110 IIDKTIIGDF 120 QKEQKKFVEE 130 QHTKKSEAAV 140 PPWVDSNDEE 150 TIQQQVLALS 160 ADKRNFLRDP 170 PAGVQFNFDF 180 DQMYPVALVM 190 LQEDELLSRM 200 RFALVPKLVK 210 EEVFWRNYFY 220 RVSLIKQSAQ 230 LTALAAQQQA 240 AGKEEKSRGR 250 EDESPLTEAV 260 RPKTPPVVIK 270 SQLKTQEDEE 280 EISTSPGVSE 290 FVSDAFDACN 300 LDQEDLRKEM 310 EQLVLDKKEQ 320 ETVVLEEDSA 330 DWEKELQQEL 340 QEYEVVTESE 350 KRDENWDKEI EKMLQEEN

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0009898 cytoplasmic side of plasma membrane
Cellular Component GO:0005829 cytosol
Cellular Component GO:0030425 dendrite
Cellular Component GO:0005794 Golgi apparatus
Cellular Component GO:0030426 growth cone
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0043204 perikaryon
Cellular Component GO:0048471 perinuclear region of cytoplasm
Cellular Component GO:0045211 postsynaptic membrane
Cellular Component GO:0042734 presynaptic membrane
Cellular Component GO:0045202 synapse
Biological Process GO:0071364 cellular response to epidermal growth factor stimulus
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:1990314 cellular response to insulin-like growth factor stimulus
Biological Process GO:0036120 cellular response to platelet-derived growth factor stimulus
Biological Process GO:0045600 positive regulation of fat cell differentiation
Biological Process GO:0048172 regulation of short-term neuronal synaptic plasticity
Biological Process GO:0038203 TORC2 signaling

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.