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Overview

Uniprot IDA0A287AXC0
Protein NameTranslational activator of cytochrome c oxidase 1
Gene NameTACO1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
129 ALKMEKTKDIHLLYE

Function

Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1

Protein Sequence

10 MAAWAVVNLS 20 RAAARCLRAR 30 DPGVREALLR 40 ASQSEPPDWS 50 FAWGRMLHVT 60 AAVPAGHNKW 70 SKVRHIKGPK 80 DTERSRIFSK 90 LSLSIRLAVK 100 EGGPNPDLNS 110 NLASILEVCR 120 SKHMPKSTME 130 AALKMEKTKD 140 IHLLYEGRGP 150 GGSSLLIEAL 160 SNSGSKCLSD 170 IKHILNKNGG 180 MMAEGARHFF 190 DKKGVIVVGV 200 EDREKKAVNL 210 ERALELAIEA 220 GAEDVKETED 230 EEEKNIFKVS 240 GKLGPASLRF 250 FFPVPGVREL 260 KSSHITQTVI 270 SEYWIGLTLL 280 RTMSTIQNME 290 HLSLPVKTQT 300 QWNATVIPFR 310 FCKLLSGFVV 320 LPPYLQTFLC S

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005739 mitochondrion
Molecular Function GO:0097177 mitochondrial ribosome binding
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0019843 rRNA binding
Biological Process GO:0070131 positive regulation of mitochondrial translation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.