Search Results
Overview
| Uniprot ID | A0A287AXJ3 |
|---|---|
| Protein Name | F-actin-capping protein subunit beta |
| Gene Name | CAPZB |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 145 | GDGSKKIKGCWDSIH |
| 159 | HVVEVQEKSSGRTAH |
| 235 | LNEIYFGKTKDIVNG |
| 237 | EIYFGKTKDIVNGLR |
| 252 | SVQTFADKSKQEALK |
| 254 | QTFADKSKQEALKND |
| 259 | KSKQEALKNDLVEAL |
| 267 | NDLVEALKRKQQC** |
| 57 | ARDKVVGKDYLLCDY |
| 95 | MPSARLRKLEVEANN |
Function
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments
Protein Sequence
10
QSDQQLDCAL
20
DLMRRLPPQQ
30
IEKNLSDLID
40
LVPSLCEDLL
50
SSVDQPLKIA
60
RDKVVGKDYL
70
LCDYNRDGDS
80
YRSPWSNKYD
90
PPLEDGAMPS
100
ARLRKLEVEA
110
NNAFDQYRDL
120
YFEGGVSSVY
130
LWDLDHGFAG
140
VILIKKAGDG
150
SKKIKGCWDS
160
IHVVEVQEKS
170
SGRTAHYKLT
180
STVMLWLQTN
190
KSGSGTMNLG
200
GSLTRQMEKD
210
ETVSDCSPHI
220
ANIGRLVEDM
230
ENKIRSTLNE
240
IYFGKTKDIV
250
NGLRSVQTFA
260
DKSKQEALKN
270
DLVEALKRKQ
QC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0008290 | F-actin capping protein complex |
| Molecular Function | GO:0003779 | actin binding |
| Biological Process | GO:0030036 | actin cytoskeleton organization |
| Biological Process | GO:0051016 | barbed-end actin filament capping |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.