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Overview

Uniprot IDA0A287AZ09
Protein NameGeneral vesicular transport factor p115
Gene NameUSO1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
503 SYTKEKLKQLIEKRI
556 HEFTKLVKELEGVIT
564 ELEGVITKAIHKSSE

Function

General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity

Protein Sequence

10 MIEEMLCVLS 20 NHYLRNIAWK 30 WVFKLWNTLF 40 MFYKQIEENS 50 TRQSEDLGSQ 60 FTEIFIKQQE 70 NVTLLLSLLE 80 EFDFHVRWPG 90 VKLLTSLLKQ 100 LGPQVQQIIL 110 VSPMGVSRLM 120 DLLADSREVI 130 RNDGVLLLQA 140 LTRNNGAIQK 150 IVAFENAFER 160 LLDIITEEGN 170 SDGGIVVEDC 180 LILLQNLLKN 190 NNSNQNFFKE 200 GSYIQRMKPW 210 FEVGDENSGW 220 SAQKVTNLHL 230 MLQLVRVLVS 240 PNNPPGATSS 250 CQKAMFQCGL 260 LQQLCTILMA 270 TGVPADILTE 280 TINTVSEVIR 290 GCQVNQDYFA 300 SVNAPSNPPR 310 PAIVVLLMSM 320 VNERQPFVLR 330 CAVLYCFQCF 340 LYKNQKGQGE 350 IVSTLLPSTI 360 DATGISVSAG 370 QLLCGGLFST 380 DSLSNWCAAV 390 ALAHALQENA 400 TQKEQLLRVQ 410 LATSIGNPPV 420 SLLQQCTNIL 430 SQGSKIQTRV 440 GLLMLLCTWL 450 SNCPIAVTHF 460 LHNSANVPFL 470 TGQIAENLGE 480 EEQLVQGLCA 490 LLLGISIYFN 500 DNSLESYTKE 510 KLKQLIEKRI 520 GKENFIEKLG 530 FISKHEFYSR 540 ASQKPQPNFP 550 SPEYMIFDHE 560 FTKLVKELEG 570 VITKAIHKSS 580 EEDKKEEEVK 590 KTLEQHDSIV 600 THYKNMIREQ 610 DLQLEELKQQ 620 ISTLKCQNEQ 630 LQTAVTQQVS 640 QIQQHKDQYN 650 LLKVQLGKDN 660 QPQGSYNDGS 670 QMNGIQPEEI 680 GRLREEIEEL 690 KSNQELLQNQ 700 LAEKDSLIEN 710 LKSSQPSPGA 720 NEESSATDSA 730 RDSEQIADLK 740 QELATLKSQL 750 NSQSIEITKL 760 QTEKQELLQK 770 TEAFAKSVPE 780 PEQSETVTAA 790 KATDVEGRLS 800 ALLQETKELK 810 NEIKALSEER 820 TAIKEQLDAS 830 NSTIAILQNE 840 KNKLEVDITD 850 SKKNKTIFWC 860 CWLIRIRKYF H

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0000139 Golgi membrane
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0048280 vesicle fusion with Golgi apparatus

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.