Search Results
Overview
| Uniprot ID | A0A287AZ11 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | NFIC |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 73 | RLLAKLRKDIRPECR |
| 90 | FVLAITGKKAPGCVL |
| 91 | VLAITGKKAPGCVLS |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
MDEFHPFIEA
20
LLPHVRAFAY
30
TWFNLQARKR
40
KYFKKHEKRM
50
SKDEERAVKD
60
ELLGEKAEVK
70
QKWASRLLAK
80
LRKDIRPECR
90
EDFVLAITGK
100
KAPGCVLSNP
110
DQKGKMRRID
120
CLRQADKVWR
130
LDLVMVILFK
140
GIPLESTDGE
150
RLVKAAQCGH
160
PVLCVQPHHI
170
GVAVKELDLY
180
LAYFVRERDT
190
TDFQESFVTS
200
GVFSVTELIQ
210
VSRTPVVTGT
220
GPNFSLGELQ
230
GHLAYDLNPA
240
STGMRRTLPS
250
TSSSGSKRHK
260
SGSMEEDVDT
270
SPGGDYYTSP
280
SSPTSSNRNW
290
TEDMEGGISS
300
PVKKTEMDKS
310
PFNSPSPQDS
320
PRLSSFTQHH
330
RPVIAVHSGI
340
ARSPHPSSAL
350
HFPTTSILPQ
360
TASTYFPHTA
370
IRYPPHLNPQ
380
DPLKDLVSLA
390
CDPASQQPGP
400
PTLRPARPLQ
TVPLWD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.