Search Results

Overview

Uniprot IDA0A287AZS0
Protein NameProtein PML
Gene NamePML
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
423 TATPQKRKSCQTEAP

Function

No function data available.

Protein Sequence

10 MEEEFQFLRC 20 QGCRKEAKCP 30 KLLPCLHTLC 40 SGCLPQPGLQ 50 CPICQAPWPQ 60 GADTQALDNV 70 FFESLQRRLS 80 VYRQIMDSQA 90 LCTRCKEPAN 100 YWCFECEQLL 110 CAKCVEAHQW 120 FLKHEARPLA 130 ELRSQSVGEF 140 LDCTRKSNNI 150 FCSNPNHRSP 160 ALTSIYCRGC 170 SKPLCCSCAL 180 LDTSHSELKC 190 DIGMEIQQRQ 200 EELDTMTQAL 210 QEQDHAFGAA 220 QAQMRSAVSQ 230 LGRVRTDTEE 240 LIHARVRQVV 250 AHVLAQEQEL 260 LEGVNARYQR 270 DYEEIASQLS 280 RLDAVLQRIR 290 VGSALVQRMK 300 RYASDQEVLD 310 MHSFLRQALH 320 SLSQEEPQKL 330 RAAVRTDSFD 340 EFKVRLQDLV 350 SCITQGTDAA 360 VSRRASPEAT 370 STPRDTSDVD 380 LPEEVQRAQG 390 QTPELAVVQP 400 VPGAHPVPVY 410 AYSIKDPSCR 420 EESSSTATPQ 430 KRKSCQTEAP 440 RKVIKMESEV 450 EEERARNSPE 460 QPRPSTSKAV 470 SPPHLDGPLS 480 PKSPTKGNEL 490 FWPDSNHVTG 500 NNPGEAEERV 510 VVISSSEDSD 520 AENSDNSSSE 530 ASDLQLEGPS 540 SLGVLDESLI 550 NSGAEDRPLV 560 FFDLKIDSET 570 QKISQLAAVN 580 QESQFRMLIQ 590 PEAFTIRSKA 600 VSLEVGLQHF 610 LHFLGNMRQP 620 ILACYKLWGP 630 GLPSLFRALE 640 DMNRLQEFRK 650 AISGFLAILP 660 LIRECVPGAS 670 SFKLKNLAET 680 YLARNMNETR 690 SALASVVTMR 700 DLCRLLEVTP 710 GPQLGPHIHS 720 FSCLQCFSSL 730 QPLVRAAVLP 740 RAKARLLALH 750 KVSFLELVTA 760 HHHDPQEGLK 770 KYNCFLSPQS 780 PSSPPTQSAF 790 NLQALGTYFD 800 KGLREGLAST 810 KAEGSSSLLT 820 DHSLVERASQ ES

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000781 chromosome, telomeric region
Cellular Component GO:0005829 cytosol
Cellular Component GO:0031901 early endosome membrane
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0016363 nuclear matrix
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0016605 PML body
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0042803 protein homodimerization activity
Molecular Function GO:0046332 SMAD binding
Molecular Function GO:0032183 SUMO binding
Molecular Function GO:0019789 SUMO transferase activity
Molecular Function GO:0003712 transcription coregulator activity
Molecular Function GO:0031625 ubiquitin protein ligase binding
Molecular Function GO:0061659 ubiquitin-like protein ligase activity
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0030330 DNA damage response, signal transduction by p53 class mediator
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0032469 endoplasmic reticulum calcium ion homeostasis
Biological Process GO:0043153 entrainment of circadian clock by photoperiod
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0010761 fibroblast migration
Biological Process GO:0045087 innate immune response
Biological Process GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0032691 negative regulation of interleukin-1 beta production
Biological Process GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0090402 oncogene-induced cell senescence
Biological Process GO:0030578 PML body organization
Biological Process GO:0045893 positive regulation of DNA-templated transcription
Biological Process GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
Biological Process GO:0048146 positive regulation of fibroblast proliferation
Biological Process GO:1901798 positive regulation of signal transduction by p53 class mediator
Biological Process GO:0032206 positive regulation of telomere maintenance
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0034504 protein localization to nucleus
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0010522 regulation of calcium ion transport into cytosol
Biological Process GO:0030155 regulation of cell adhesion
Biological Process GO:2000779 regulation of double-strand break repair
Biological Process GO:0034097 response to cytokine
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0044790 suppression of viral release by host

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.